ACE inhibitor

ACE inhibitor
angiotensin-converting enzyme inhibitor: any one of a group of drugs used in the treatment of raised blood pressure and heart failure. ACE inhibitors act by interfering with the action of the enzyme that converts the inactive angiotensin I to the powerful artery constrictor angiotensin II. The absence of this substance allows arteries to widen and the blood pressure to drop. ACE inhibitors are administered by mouth; they include captopril, enalapril, perindopril (Coversyl), and ramipril (Tritace). Possible side-effects include weakness, dizziness, loss of appetite, and skin rashes.

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  • ACE inhibitor — ACE inhibitors, or inhibitors of Angiotensin Converting Enzyme, are a group of pharmaceuticals that are used primarily in treatment of hypertension and congestive heart failure, in some cases as the drugs of first choice.Clinical useIndications… …   Wikipedia

  • ACE inhibitor — (angiotensin converting enzyme inhibitor) group of drugs which lower blood pressure by inhibiting the angiotensin converting enzyme (Medicine) …   English contemporary dictionary

  • ACE inhibitor — [ā΄sē΄ē′, ās] n. [a( ngiotensin ) c( onverting) e( nzyme)] any of a class of drugs, including captopril, that inhibit or block the action of an enzyme (ACE) that produces the powerful vasoconstrictor angiotensin, used to treat high blood pressure …   English World dictionary

  • ACE inhibitor — A drug that inhibits ACE (angiotensin converting enzyme) which is important to the formation of angiotensin II. Angiotensin II causes arteries in the body to constrict and thereby raises the blood pressure. ACE inhibitors lower the blood pressure …   Medical dictionary

  • ACE inhibitor — noun an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to …   Useful english dictionary

  • ACE inhibitor — Angiotensin converting enzyme inhibitor. A drug that is used to lower blood pressure. An ACE inhibitor is a type of antihypertensive agent. Also called angiotensin converting enzyme inhibitor …   English dictionary of cancer terms

  • ACE inhibitor — ACE′ inhib itor [[t]eɪs, ˈeɪˈsiˈi[/t]] n. pha med any of a group of vasodilator drugs used in the treatment of hypertension and heart failure • Etymology: 1980–85; A(ngiotensin) C(onverting) E(nzyme) …   From formal English to slang

  • ACE inhibitor — noun Etymology: angiotensin converting enzyme Date: 1982 any of a group of antihypertensive drugs (as captopril) that relax arteries and promote renal excretion of salt and water by inhibiting the activity of angiotensin converting enzyme …   New Collegiate Dictionary

  • ACE inhibitor — /ays, ay see ee / any of a group of vasodilator drugs used in the treatment of hypertension and heart failure. [1980 85; A(ngiotensin) C(onverting) E(nzyme)] * * * …   Universalium

  • ACE inhibitor — noun / eɪs ən.hɪ.bɪ.toɹ/lang=en any one of a class of drugs, including captopril and enalpapril, that cause the arteries to widen by preventing the synthesis on angiotensin: used to treat high blood pressure and heart failure …   Wiktionary